PLLA Collagen Stimulators in London by Dr Priya Verma

Unlike dermal fillers that provide immediate volume, PLLA collagen stimulators such as Sculptra® and Juläine™ deliver skin strengthening results that develop gradually as new collagen forms.

You may notice early improvement in skin tone and texture from six weeks after your first session, with the most visible results typically appearing between three and six months. This timeframe reflects your body’s natural collagen-building cycle. 

Results from PLLA collagen stimulator treatments such as Sculptra® and Juläine™ are impressively long-lasting — typically up to two years, and often longer with maintenance.

As the treatment works by stimulating your skin’s own collagen production, the results develop gradually and strengthen over time. Most patients notice visible improvement from around six to twelve weeks, with optimal results emerging after a full course of sessions.

Because your new collagen is produced naturally by your own skin, the improvement fades slowly and gracefully. Periodic maintenance treatments help sustain firmness, definition and texture for consistently rejuvenated results.

Downtime following Sculptra® or Juläine™ treatment is minimal. You may experience mild swelling, tenderness or bruising at the injection sites, which typically settles within a few days.

Most patients return to normal activities immediately and we provide detailed aftercare advice following treatment to reduce downtime and optimise your results.

As with any medical procedure, there are risks, but these will be discussed with you during your consultation. When treatments like PLLA are performed by a qualified medical professional, collagen stimulators are extremely safe and supported by extensive clinical data.

At the Dr Priya Verma Clinic, all procedures are performed by either Dr Verma - a fully qualified GP and aesthetic doctor with advanced postgraduate training in regenerative injectables or a practitioner trained by Dr Verma herself. Treatments are carried out in our Save Face accredited medical clinic, ensuring the highest standards of hygiene, safety and patient care.

Both Sculptra® and Juläine™ are biocompatible and biodegradable, meaning the product is naturally broken down by the body over time. Adverse reactions are rare when the treatment is performed using correct dilution and technique. Dr Verma’s meticulous, anatomy-led approach ensures your experience is both safe and seamless.

Yes, PLLA collagen stimulators can safely be combined with dermal fillers and Botox® as part of a holistic, layered rejuvenation plan.

While PLLA injectables such as Sculptra® and Juläine™ rebuild the skin’s underlying collagen structure for long-term firmness, fillers can refine contour and restore immediate volume, and Botox® helps soften dynamic lines.

At Dr Priya Verma Clinic, combination treatments are precisely planned and timed for optimal synergy - enhancing facial harmony and ensuring results remain natural and balanced.

The number of sessions required depends on your age, skin quality, and degree of collagen loss. Most patients require a course of two to three sessions, spaced four to six weeks apart. Each session builds progressively on the last, allowing collagen to develop naturally and evenly.

Dr Verma will design a bespoke treatment plan tailored to your skin condition and aesthetic goals. Once your desired result is achieved, maintenance treatments are recommended to help preserve firmness and structure over time.

PLLA collagen stimulators are suitable for men and women who wish to restore skin firmness, improve texture and elasticity, and address age-related volume changes through a gradual, regenerative approach.

Suitable candidates are those showing early to moderate signs of skin laxity, hollowing or thinning. PLLA treatments are ideal for those looking to enhance their natural facial structure over time, as opposed to seeking instant volumisation which dermal fillers are best suited for. PLLA treatments are particularly effective for improving skin density, redefining contours, and achieving long-term rejuvenation with subtle, progressive results.

During your consultation, Dr Priya Verma will conduct a detailed assessment of your skin, facial anatomy and aesthetic goals to determine whether PLLA, dermal fillers, or a combination of both is best suited to achieve a balanced and harmonious result.

Both dermal fillers and PLLA collagen stimulators work in very different ways and often complement each other.

Dermal fillers are synthetic gels made from hyaluronic acid and provide precise, immediate volume and contour enhancement. They are particularly suited to defining the cheeks, lips, chin and jawline, or replacing lost volume in areas such as the mid-face and tear troughs. PLLA collagen stimulators, such as Sculptra® and Juläine™, are powder-based substances which when mixed with salty water, turn into a cloudy watery consistency which can be used to strengthen the skin, improving laxity and restoring bounce in the skin. PLLA biostimulators offer a more regenerative approach - stimulating your body’s own collagen for subtle, long-lasting improvement in skin thickness, elasticity and support.

For patients seeking a more natural and gradual rejuvenation without instant volume, PLLA injectables can be an excellent alternative or addition to fillers, depending on your goals. We will discuss each option with you during your Consultation so that you can make an informed choice based on your aesthetic concerns and goals.

Results from PLLA collagen stimulators are not permanent, but they are among the longest-lasting non-surgical rejuvenation options available.

Because the results come from your body’s own collagen production, they fade gradually and naturally as collagen turnover continues with age. Most patients enjoy results for up to two years, with subtle residual improvement often lasting beyond this timeframe.

Maintenance sessions can extend longevity, helping to preserve the firmness, definition and smoothness achieved.

Unlike hyaluronic acid dermal fillers, PLLA (Poly-L-Lactic Acid) collagen stimulators cannot be immediately dissolved. This is because PLLA works by stimulating your own collagen production over time. Once new collagen has formed, it cannot be “reversed,” but it does gradually and naturally break down as part of the body’s normal ageing process. As results are gradual, subtle and natural, dissatisfaction from PLLA results is extremely uncommon.

At the Dr Priya Verma Clinic, we always begin with a conservative, stepwise approach to ensure natural, balanced results that develop progressively. Each session is carefully planned and reviewed with you so that you are well informed before proceeding with treatment.